Cancer genomics

Evidence-based point of care tools for health care providers on cancer genomic topics.

BRCA1/BRCA2 Hereditary Breast and Ovarian Cancer Syndrome (Updated July 2019)

A two-part (I, II) point of care tool to identify individuals likely to benefit from a genomic risk assessment (I) and those predicted to be at increased risk to carry a mutation in the BRCA1 or BRCA2 genes (II).

General hereditary cancer (Updated Jan 2020)

A point of care tool containing general family history red flags to identify patients with risk of a hereditary cancer syndrome most likely to benefit from referral to genetics.

Lynch Syndrome (Updated Oct 2014)

A two-part (I, II) point of care tool containing three questions to stratify an individual’s risk for hereditary colorectal cancer and to identify those that likely to benefit from a genomic assessment (I), as well as those at high risk to carry a mutation in a Lynch syndrome gene (II).  

Renal Cell Cancers (Updated 2013)

Practical guide to identify those patients most likely to benefit from a genomic assessment for hereditary renal cell cancer syndromes e.g. Von Hippel-Lindau syndrome, hereditary papillary renal cell cancer.

GEC-KO aims to aid the practicing non-genetics health professional by providing informed opinions regarding genetic/genomic conditions, services and technologies that have been developed in a rigorous and evidence-based manner with periodic updating.  The content on the GEC-KO site is for educational purposes only.  No resource should be used as a substitute for clinical judgement.  GEC-KO assumes no responsibility or liability resulting from the use of information contained herein.