GEC-KO Messengers

GEC-KO Messengers are comprehensive summaries for healthcare providers on genetic disorders, technologies or topics.  These interactive summaries are found in the left-hand menu and can be viewed in page or the whole PDF version can be downloaded. For access to a more concise summary, view or download a GEC-KO on the run found in the left-hand menu. Where possible, a point-of-care (POC) tool on the same subject will also be available in the top menu.

GEC-KO Messengers and GEC-KO on the run are written by a team that includes genetic counsellors, geneticists and genetic researchers. All are reviewed by a family physician.  They are evidence-based and referenced, and feature a ‘Bottom line’ with recommendations.  They were developed as a ‘spin-off’ of the successful Gene Messengers which were part of the GenetiKit project.  Findings from this study were published and can be found in Carroll JC, Wilson BJ, Allanson J, Grimshaw J, Blaine SM, Meschino WS, Permaul JA, Graham ID. GenetiKit: a randomized controlled trial to enhance delivery of genetics services by family physicians. Fam Pract 2011; 28(6): 615-23.

As we are busy developing content, we are happy to hear from our users about suggested topics for GEC-KO Messenger.  If there is content you feel should be prioritized to better incorporate genomic medicine in your practice, please do not hesitate to contact us and let us know.


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Autism spectrum disorder  | ASD | ASDplus | Complex | chromosomal microarray | fragile X syndrome | GEC-KO Messenger (2017)


Colorectal Cancer | Lynch syndrome | Colorectal | Hereditary non-polyposis colorectal cancer (HNPCC) syndrome | GEC-KO Messenger (2014)

Consanguinity | Preconception  counselling | Ethnicity-based screening | GEC-KO Messenger (2014)


Epilepsy | Seizures | GEC-KO Messenger (2018)


Factor V Leiden | Thrombophilia | Clotting disorder | GEC-KO Messenger (2014)

Familial hypercholesterolemia | FH | cholesterol | dyslipidemia | cardiovasular disease | GEC-KO Messenger (2016)



Hereditary Breast and Ovarian Cancer Syndrome | HBOC | BRCA1 | BRCA2 | GEC-KO Messenger (2016)

Hereditary Hemochromatosis | HH | HFE | Iron Overload | C282Y | GEC-KO Messenger (2013)


Lynch Syndrome | LS | Colon | Colorectal | Hereditary non-polyposis colorectal cancer (HNPCC) syndrome | MSI | MLH | MSH | GEC-KO Messenger (2014)



Multiple Sclerosis | MS | Demyelinating | Complex inheritance | Suceptibility | GEC-KO Messenger (2014)



Thrombophilia | Factor V Leiden | Clotting disorder | GEC-KO Messenger (2014)



Currently, the website is attempting to meet the information needs of healthcare providers. As a result, when choosing content and terminology for the site, we have assumed that the reader has a certain amount of medical knowledge.

Healthcare providers must use their own clinical judgment in addition to the information presented herein. The authors assume no responsibility or liability resulting from the use of information on this website.

All healthcare providers using this site are encouraged to consult local genetics clinics, medical geneticists, or specialists for clarification of questions that arise relating to specific patient problems.

External links are selected and reviewed at the time a page is published. However, GEC-KO is not responsible for the content of external websites. The inclusion of a link to an external website from GEC-KO should not be understood to be an endorsement of that website or the site’s owners (or their products/services).

We strive to provide accurate, timely, unbiased and up-to-date information on this site, and make every attempt to ensure the integrity of the site. However, it is possible that the information contained here may contain inaccuracies or errors for which neither GEC-KO nor its funding agencies assume responsibility.